Novel Hepatitis E Virus Genotype in Norway Rats, Germany
نویسندگان
چکیده
Human hepatitis E virus infections may be caused by zoonotic transmission of virus genotypes 3 and 4. To determine whether rodents are a reservoir, we analyzed the complete nucleotide sequence of a hepatitis E-like virus from 2 Norway rats in Germany. The sequence suggests a separate genotype for this hepatotropic virus.
منابع مشابه
No Evidence for Hepatitis E Virus Genotype 3 Susceptibility in Rats
2. Johne R, Plenge-Bonig A, Hess M, Ulrich RG, Reetz J, Schielke A. Detection of a novel hepatitis E–like virus in faeces of wild rats using a nested broad-spectrum RT-PCR. J Gen Virol. 2010;91:750–8. http://dx.doi.org/10.1099/vir.0.016584-0 3. Li TC, Yoshimatsu K, Yasuda SP, Arikawa J, Koma T, Kataoka M, et al. Characterization of self-assembled virus-like particles of rat hepatitis E virus ge...
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Hepatitis E virus (HEV) is a causative agent of hepatitis E. Recently, a novel hepatitis E-like virus was isolated from Norway rats in Germany. However, the antigenicity, pathogenicity and epidemiology of this virus are unclear because of the lack of a cell-culture system in which to grow it. In this study, an N-terminally truncated ORF2 protein was expressed in insect Tn5 cells using a recombi...
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عنوان ژورنال:
دوره 17 شماره
صفحات -
تاریخ انتشار 2010